PUBLICATIONS

Publications in peer reviewed journals

  1. Pöhlmann, C., M. Thomas, S. Förster, M. Brandt, M. Hartmann, A. Bleich, and F. Gunzer. 2013. Improving health from the inside: use of engineered intestinal microorganisms as in situ cytokine delivery system. Bioengineered May-Jun;4(3):172-179.
  2. Michael S., L. M. Keubler, A. Smoczek, M. Meier, F. Gunzer, C. Pöhlmann, U. Krause-Buchholz, H. J. Hedrich, and A. Bleich. 2013. Quantitative phenotyping of inflammatory bowel disease in the IL10-deficient mouse by use of non-invasive magnetic resonance imaging. Inflamm. Bowel Dis. Jan;19(1):185-193.
  3. Zschüttig, A., K. Zimmermann, J. Blom, A. Goesmann, C. Pöhlmann, and F. Gunzer. 2012. Identification and characterization of microcin S, a new antibacterial peptide produced by probiotic Escherichia coli G3/10. PLoS ONE 7(3):e33351; 1-9.
  4. Pöhlmann, C., M. Brandt, D. S. Mottok, A. Zschüttig, J. W. Campbell, F. R. Blattner, D. Frisch, and F. Gunzer. 2012. Periplasmic delivery of biologically active human interleukin 10 in Escherichia coli via a Sec-dependent signal peptide. J.Mol.Microb.Biotech. 21;22(1) 1-9.
  5. Alter, T., B. Appel, E. Bartelt, R. Dieckmann, C. Eichhorn, R. Erler, C. Frank, G. Gerdts, F. Gunzer, S. Hühn, J. Neifer, B. Oberheitmann, and E. Strauch. 2011. Vibrio-Infektionen durch Lebensmittel und Meerwasser. Das Netzwerk „VibrioNet“ stellt sich vor. Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz 54:1235-1240
  6. Friedrich, T., S. Rahman, W. Weigel, W. Rabsch, A. Fruth, E. Ron, F. Gunzer, T. Dandekar, J. Hacker, T. Müller, and U. Dobrindt. 2010. High-throughput microarray technology in diagnostics of enterobacteria based on genome-wide probe selection and regression analysis. BMC Genomics 11, 591.
  7. Weiss, S. M., M. Ladwein, D. Schmidt, J. Ehinger, S. Lommel, K. Städing, U. Beutling, A. Disanza, R. Frank, L. Jänsch, G. Scita, F. Gunzer, K. Rottner, and T. E. B. Stradal. 2009. IRSp53 links the enterohemorrhagic E. coli effectors Tir and EspFU for actin pedestal formation. Cell Host Microbe 5; 244-258.
  8. Krämer, S., G. Sellge, A. Lorentz, D. Krüger, M. Schemann, K. Feilhauer, F. Gunzer, and S. C. Bischoff. 2008. Selective activation of human intestinal mast cells by Escherichia coli hemolysin. J.Immunol. Jul. 15; 181(2): 1438-1445
  9. Bleich, A., J. P. Sundberg, A. Smoczek, R. V. Wasielewski, M. F. de Buhr, L. M. Janus, G. Julga, S. N. Ukena, H. J. Hedrich, and F. Gunzer. 2008. Sensitivity to Escherichia coli Nissle 1917 in mice is dependent on environment and genetic background. Int.J.Exp.Path. 89: 45-54.
  10. Ukena, S. N., A. Singh, U. Dringenberg, R. Engelhardt, U. Seidler, W. Hansen, A. Bleich, D. Bruder, G. Rogler, S. Suerbaum, J. Buer, F. Gunzer, and A. M. Westendorf. 2007. Probiotic Escherichia coli Nissle 1917 inhibits leaky gut by enhancing mucosal integrity. PLoS ONE 12;2(12):e1308; 1-9.
  11. Coldewey, S. M., M. Hartmann, D. S. Schmidt, U. Engelking, S. N. Ukena, and F. Gunzer. 2007. Impact of the rpoS genotype for acid resistance patterns of pathogenic and probiotic Escherichia coli. BMC Microbiol. Mar. 26;7:21.
  12. Ukena, S. N., A. M. Westendorf, W. Hansen, M. Rohde, R. Geffers, S. Coldewey, S. Suerbaum, J. Buer, and F. Gunzer. 2005. The host response to the probiotic Escherichia coli strain Nissle 1917: Specific up-regulation of the proinflammatory chemokine MCP-1. BMC Med.Genet. Dec. 13;6:43.
  13. Reuter, C. W., M. A. Morgan, F. C. Bange, F. Gunzer, M. Eder, B. Hertenstein, and A. Ganser. 2005. Candida kefyr as an emerging pathogen causing nosocomial bloodstream infections in neutropenic leukemia patients. Clin.Infect.Dis. 41:1365-1366.
  14. Sun, J., F. Gunzer, A. M. Westendorf, J. Buer, M. Scharfe, F. Gößling, H. Blöcker, and A. P. Zeng. 2005. Genomic peculiarity of coding sequences and metabolic potential of probiotic Escherichia coli strain Nissle 1917 inferred from raw genome data. J.Biotechnol. 117:147-161.
  15. Westendorf, A. M., F. Gunzer, S. Deppenmeier, J. K. Hunger, M. A. Schmidt, J. Buer, and D. Bruder. 2005. Intestinal immunity of E. coli NISSLE 1917: A safe carrier for therapeutic molecules. FEMS Immunol.Med.Microbiol. 43:373-384
  16. Westendorf, A. M., M. Templin, R. Geffers, S. Deppenmeier, A. D. Gruber, M. Probst-Kepper, W. Hansen, R. S. Liblau, F. Gunzer, D. Bruder, and J. Buer. 2005.CD4+ T Cell mediated intestinal immunity: chronic inflammation versus immune regulation. Gut 54:60-69.
  17. Ma H. W., B. Kumar, U. Ditges, F. Gunzer, J. Buer, and A. P. Zeng. 2004. An extended transcriptional regulatory network of Escherichia coli and its structural analysis. Nucleic Acids Res. 32:6643-6649.
  18. Pape, L., F. Gunzer, S. Ziesing, A. Pape, G. Offner, and J. H. Ehrich. 2004. Bacterial pathogens, resistance patterns and treatment options in community acquired pediatric urinary tract infection. Klin.Pädiatr. 216:83-86.
  19. Pulz, M., A. Matussek, M. Monazahian, A. Tittel, E. Nikolic, M. Hartmann, T. Bellin, J. Buer, and F. Gunzer. 2003. Comparison of a Shiga toxin ELISA and two different types of PCR for detection of Shiga toxin-producing Escherichia coli in human stool specimens. J.Clin.Microbiol. 41:4671-4675.
  20. Matussek, A., J. Lauber, A. Bergau, W. Hansen, M. Rohde, K. E. J. Dittmar, M. Gunzer, M. Mengel, P. Gatzlaff, M. Hartmann, J. Buer, and F. Gunzer. 2003. Molecular and functional analysis of Shiga toxin induced response patterns in human vascular endothelial cells. Blood. 102:1323-1332.
  21. Gunzer, F., I. Hennig-Pauka, K. H. Waldmann, R. Sandhoff, H. J. Gröne, H. H. Kreipe, A. Matussek, and M. Mengel. 2002. Gnotobiotic piglets develop thrombotic microangiopathy after oral infection with enterohemorrhagic Escherichia coli. Am.J.Clin.Pathol. 118:364-375.
  22. Bellin, T., M. Pulz, A. Matussek, H. G. Hempen, and F. Gunzer. 2001. Rapid detection of enterohemorrhagic Escherichia coli by real-time PCR with fluorescent hybridization probes. J.Clin.Microbiol. 39:370-374.
  23. Dogan, S., F. Gunzer, H. Guenay, G. Hillmann, and W. Geurtsen. 2000. Infection of primary human gingival fibroblasts by Porphyromonas gingivalis and Prevotella intermedia. Clin.Oral Investig. 4:35-41.
  24. Bange, F. C., S. Ruttkowski, M. Kist, S. Bereswill, D. Meyer, R. E. Schmidt, H. Tillmann, I. Schedel, M. P. Manns, and F. Gunzer. 2000. Clinical microbiological case: a 35-year-old HIV-positive man with intermittent fever and chronic diarrhea. Clin.Microbiol.Infect. 6:613-616.
  25. Gunzer, F., U. Bohn, S. Fuchs, I. Mühldorfer, J. Hacker, S. Tzipori, and A. Donohue-Rolfe. 1998. Construction and characterization of an isogenic slt-II deletion mutant of enterohemorrhagic Escherichia coli. Infect.Immun. 66:2337-2341.
  26. Datz, M., S. Janetzki-Mittmann, S. Franke, F. Gunzer, H. Schmidt, and H. Karch. 1996. Analysis of the enterohemorrhagic Escherichia coli O157 DNA region containing lambdoid phage gene p and Shiga-like toxin structural genes. Appl.Environ.Microbiol. 62:791-797.
  27. Tzipori, S., F. Gunzer, M. S. Donnenberg, L. de Montigny, J. B. Kaper, and A. Donohue-Rolfe. 1995. The role of the eaeA gene in diarrhea and neurological complications in a gnotobiotic piglet model of enterohemorrhagic Escherichia coli infection. Infect.Immun. 63:3621-3627.
  28. Franke, S., F. Gunzer, L. H. Wieler, G. Baljer, and H. Karch. 1995. Construction of recombinant Shiga-like toxin-IIv (SLT-IIv) and its use in monitoring the SLT-IIv antibody status of pigs. Vet.Microbiol. 43:41-52.
  29. Gunzer, F. and H. Karch. 1993. Expression of A and B subunits of Shiga-like toxin II as fusions with glutathione S-transferase and their potential for use in seroepidemiology. J.Clin.Microbiol. 31:2604-2610.
  30. Karch, H., H. Böhm, H. Schmidt, F. Gunzer, S. Aleksic, and J. Heesemann. 1993. Clonal structure and pathogenicity of Shiga-like toxin-producing, sorbitol-fermenting Escherichia coli O157:H-. J.Clin.Microbiol. 31:1200-1205.
  31. Gunzer, F., H. Böhm, H. Rüssmann, M. Bitzan, S. Aleksic, and H. Karch. 1992. Molecular detection of sorbitol-fermenting Escherichia coli O157 in patients with hemolytic-uremic syndrome. J.Clin.Microbiol. 30:1807-1810.

Reviews

  1. Karch, H., F. Gunzer, A. Schwarzkopf, H. Schmidt, und M. Bitzan. 1993. Molekularbiologie und pathogenetische Bedeutung von Shiga- und Shiga-like Toxinen. BioEng. 9:39-45.

Further publications

  1. Büttner, C., S. Leschner, S. Weiss, und F. Gunzer. 2011. Mit Bakterien gegen den Krebs – Modifizierte probiotische Bakterien für die Behandlung von soliden Tumoren. GENOMXPRESS 1.11:11-13.
  2. Schrauder, A., C. Strehlau, F. Gunzer, L. Grigull, and S. Glüer. 2001. Taenia saginata (beef tapeworm). Monatsschr.Kinderheilkd. 149:950-951.

Book chapters

  1. Schmidt, H., und F. Gunzer. 2009. Escherichia coli - Pathogenitätsfaktoren und probiotisches Potential. S. 132-143. In S. Bischoff (Hg.), Probiotika, Präbiotika und Synbiotika. Georg Thieme Verlag.
  2. Gunzer, F., I. Hennig-Pauka, K. H. Waldmann, and M. Mengel. 2003. Gnotobiotic piglets as an animal model for oral infection with O157 and non-O157 serotypes of STEC. Methods Mol.Med. 73:307-327.
  3. Gunzer, F., O. Böhler, B. Henkel, A. Schwarzkopf, H. Schmidt, H. Karch, and R. Lissner. 1994. Capability of commercial immunoglobulin preparations to react with and neutralize Shiga-like toxin II. p. 349-352. In M.A. Karmali and A.G. Goglio (ed.), Recent Advances in Verocytotoxin-producing Escherichia coli Infections. Elsevier Science B. V.